Product Name: Z-VAD-FMK
Subtitle: Cell-permeable, irreversible pan-caspase inhibitor
Biological Activity: Biological Activity of Z-VAD-FMKCell-permeable, irreversible pan-caspase inhibitor. Inhibits caspase processing and apoptosis induction in tumor cells in vitro (IC50 = 0.0015 – 5.8 mM). Active in vivo.
SMLES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)OCC1=CC=CC=C1
CAS NO: 474645-27-7
Standard In CHIKey: MIFGOLAMNLSLGH-QOKNQOGYSA-NReverse Transcriptase inhibitors
Standard InChI: InChI=1S/C22H30FN3O7/c1-13(2)19(26-22(31)33-12-15-8-6-5-7-9-15)21(30)24-14(3)20(29)25-16(17(27)11-23)10-18(28)32-4/h5-9,13-14,16,19H,10-12H2,1-4H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,19-/m0/s1
Typrof Compound:
Appearance:
Formula: C22H30FN3O7
M.Wt: 467.49
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/250/3/887
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 9.35 mg/ml in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone