Product Name: Nutlin-3a chiral
Subtitle: MDM2 inhibitor, antiproliferative and antiproapoptotic
Biological Activity: Biological Activity of Nutlin-3a chiralDescription Nutlin-3 is a small-molecule inhibitor of mouse double minute 2 (MDM2) with IC50 value of 0.09 μM. Targets MDM2 IC50 0.09 μM
SMLES: CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
CAS NO: 1207456-01-6
Standard In CHIKey: TNF-alpha inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C30H30Cl2N4O4
M.Wt: 581.49
General Tips: for obtaining a higher concentration: Please warm the tube at 37℃ for 10 minutes and/or shake it in the ultrasonic bath for a while. Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/142
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-[(4S,5R)-4,5-bis(4-chlorophenyl)-2-(4-methoxy-2-propan-2-yloxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one