Product Name: Tenovin-1
Subtitle: SIRT2 inhibitor, activates p53
Biological Activity: Biological Activity of Tenovin-1p53 activator that protects against MDM2-mediated p53 degradation. Elevates levels of p53 and p21CIP/WAF1 and induces expression from an endogenous p53-dependent promoter. Exhibits potent antiproliferative activity in vitro
SMLES: CC(=O)NC1=CC=C(C=C1)NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C
CAS NO: 273404-37-8
Standard In CHIKey: Haspin Kinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C20H23N3O2S
M.Wt: 369.5
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/1/27
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: N-[[[4-(Acetylamino)phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)benzamide