Product Name: MIRA-1
Subtitle: Restorer of wild-type p53 conformation/cellular function
Biological Activity: Biological Activity of MIRA-1Restores wild-type conformation, function and DNA binding activity to mutant p53. Induces p53 transcriptional transactivation of p21, MDM2 and PUMA, and promotes tumor cell death by apoptosis in a mutant p53-dependent manner i
SMLES: CCC(=O)OCN1C(=O)C=CC1=O
CAS NO: 842133-18-0
Standard In CHIKey: YXEWPGYLMHXLPS-UHFFFAOYSA-NAngiotensin Receptor inhibitors
Standard InChI: InChI=1S/C8H9NO4/c1-2-8(12)13-5-9-6(10)3-4-7(9)11/h3-4H,2,5H2,1H3
Typrof Compound:
Appearance:
Formula: C8H9NO4
M.Wt: 183.16
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/490
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at +4℃
Purity: >98%
Chemical Name: 1-[(1-Oxopropoxy)methyl]-1H-pyrrole-2,5-dione