Product Name: CGI-1746
Subtitle: Btk inhibitor
Biological Activity: Biological Activity of CGI-1746Description CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC50 value of 1.9 nM. Targets Btk IC50 1.9 nM
SMLES: CC1=C(C=CC=C1NC(=O)C2=CC=C(C=C2)C(C)(C)C)C3=CN(C(=O)C(=N3)NC4=CC=C(C=C4)C(=O)N5CCOCC5)C
CAS NO: 1229208-44-9
Standard In CHIKey: CXCR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C34H37N5O4
M.Wt: 579.71
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/543
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 4-tert-butyl-N-[2-methyl-3-[4-methyl-6-[4-(morpholine-4-carbonyl)anilino]-5-oxopyrazin-2-yl]phenyl]benzamide