Product Name: DMXAA (Vadimezan)
Subtitle: Tumnor vascular disrupting agent, apoptosis inducer
Biological Activity: Biological Activity of DMXAA (Vadimezan)mSTING agonist; selective for mouse STING over human STING. Induces IFN-β and cytokine production from bone marrow-derived dendritic cells. Causes tumor regression following intratumoral administration in mouse
SMLES: CC1=C(C2=C(C=C1)C(=O)C3=C(O2)C(=CC=C3)CC(=O)O)C
CAS NO: 955977-50-1
Standard In CHIKey: XGOYIMQSIKSOBS-UHFFFAOYSA-NGNRH Receptor inhibitors
Standard InChI: InChI=1S/C17H14O4/c1-9-6-7-13-15(20)12-5-3-4-11(8-14(18)19)17(12)21-16(13)10(9)2/h3-7H,8H2,1-2H3,(H,18,19)
Typrof Compound:
Appearance:
Formula: C17H14O4
M.Wt: 282.29
General Tips: for obtaining a higher concentration: Please warm the tube at 37 °C for 10 minutes and/or shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.PubMed ID:http://jpet.aspetjournals.org/content/251/2/594
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 20 mM in DMSO
Storage: Store at +4℃
Purity: >98%
Chemical Name: 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid