Product Name: PlumbaginSubtitle: Anticancer agentBiological Activity: Biological Activity of Plumbagin Anticancer agent. Induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependent p53 Ser15 phosphorylation; inhibits A549 and…
Product Name: PiplartineSubtitle: Inducer of cell-deathBiological Activity: Biological Activity of Piplartine Induces cell death and increases the level of reactive oxygen species (ROS) in cancer cells with both wild-type and…
Product Name: MatrineSubtitle: Alkaloid found in Sophora plantBiological Activity: Biological Activity of Matrine 1. Matrine has anticancer property, which include the inhibition of human osteosarcoma cells invasion and proliferation ,…
Product Name: Gambogic acidSubtitle: Caspase activator and apoptosis inducerBiological Activity: Biological Activity of Gambogic acid Apoptosis inducer in several tumor cell lines including T47D cells. Activates caspases (EC50 values are…
Product Name: EmbelinSubtitle: XIAP inhibitor,cell-permeableBiological Activity: Biological Activity of Embelin Cell-permeable, non-peptide inhibitor of X-linked inhibitor of apoptosis (XIAP) (IC50 = 4.1 μM in competition binding assay with Smac peptide);…
Product Name: DeguelinSubtitle: Anticancer and antiviral agentBiological Activity: Biological Activity of Deguelin Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC50 values…
Product Name: CisplatinSubtitle: Inhibits DNA synthesis,chemotherapy drugBiological Activity: Biological Activity of Cisplatin Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of…
Product Name: CapsaicinSubtitle: TRPV1 receptor agonistBiological Activity: Biological Activity of Capsaicin Prototypic vanilloid receptor agonist (pEC50 values are 7.97 and 7.10 at rat and human VR1 receptors respectively). Excites a…
Product Name: Betulinic acidSubtitle: Anti-HIV and antitumor compound,pentacyclic triterpenoidBiological Activity: Biological Activity of Betulinic acid Natural triterpenoid that displays anti-HIV and antitumor activity. Induces the production of reactive oxygen species…
Product Name: Atractyloside potassium saltSubtitle: ANT inhibitorBiological Activity: Biological Activity of Atractyloside potassium salt 1. Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the…