Product Name: AG 99
Subtitle: EGFR inhibitor
Biological Activity: Biological Activity of AG 99Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Blocks tyrosine phosphorylation of p145met and promotes cell death of normal and cancer cells via activa
SMLES:
CAS NO: 802906-73-6
Standard In CHIKey: USOXQZNJFMKTKJ-XVNBXDOJSA-NPhospholipase inhibitors
Standard InChI: InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+
Typrof Compound:
Appearance:
Formula: C10H8N2O3
M.Wt: 204.18
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/745
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 5 mM in ethanol and to 100 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenamide