Product Name: BIBU 1361 dihydrochloride
Subtitle: EGFR inhibitor
Biological Activity: Biological Activity of BIBU 1361 dihydrochloridePotent inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 3 nM). Displays ~ 100-fold lower potency against ErbB2 (IC50 = 290 nM) and is selective over a range of other related tyros
SMLES:
CAS NO: 511296-88-1
Standard In CHIKey: Dopamine Transporter inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H27ClFN7.2HCl
M.Wt: 516.87
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/885
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in water and to 25 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: N-(3-Chloro-4-fluorophenyl)-6-[4-[(diethylamino)methyl]-1-piperidinyl]-pyrimido[5,4-d]pyrimidin-4-amine dihydrochloride