Product Name: GSK J2
Subtitle:
Biological Activity: Biological Activity of GSK J2Inactive control of GSK J1 (Cat No.4593) (IC50 > 100 μM for inhibition of JMJD3/UTX). Cell permeable ester derivative, GSK J5, also available.
SMLES: [O-]C(CCNC1=CC(N2CCC3=CC=CC=C3CC2)=NC(C4=CC=CN=C4)=N1)=O
CAS NO: 948841-07-4
Standard In CHIKey: PI3K/Akt/mTOR_Compound_Library inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C22H23N5O2
M.Wt: 389.45
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/261/3/977
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Storage: Desiccate at RT
Purity: >98%
Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester