Product Name: HDS 029
Subtitle:
Biological Activity: Biological Activity of HDS 029Potent inhibitor of the ErbB receptor family (IC50 values are 0.3, 0.5 and 1.1 nM for ErbB1 (EGFR), ErbB4 and ErbB2 respectively). Inhibits EGF-induced erbB1 autophosphorylation in NIH3T3 cells and heregulin-stimulated ErbB a
SMLES: ClC1=CC(NC2=NC=NC3=C2C=C(NC(C#CC)=O)N=C3)=CC=C1F
CAS NO: 4727-31-5
Standard In CHIKey: Serotonin Transporter inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H11ClFN5O
M.Wt: 355.76
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/914
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 25 mM in DMSO
Storage: Store at -20℃
Purity: >98%
Chemical Name: N-(4-[(-3-Chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl-2-butynamide