Product Name: Indirubin-3-oxime
Subtitle:
Biological Activity: Biological Activity of Indirubin-3-oximeProtein kinase inhibitor; inhibits cyclin-dependent kinases (IC50 = 0.18 – 3.33 μM) and GSK-3β (IC50 = 0.19 μM). Inhibits CDK5- and GSK-3β-mediated tau phosphorylation, a process over-active in
SMLES: O=C1N=C2C(C=CC=C2)=C1C(NC3=CC=CC=C43)=C4NO
CAS NO: 869288-64-2
Standard In CHIKey: AChE inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H11N3O2
M.Wt: 277.28
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/850
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage: Store at RT
Purity: >98%
Chemical Name: 3-[1,3-Dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one