Product Name: PD 158780
Subtitle:
Biological Activity: Biological Activity of PD 158780Potent inhibitor of ErbB receptor family tyrosine kinases (IC50 values are 0.008, 49 and 52 nM for EGFR, ErbB2 and ErbB2/ErbB4 respectively) that does not inhibit FGF or PDGF-mediated tyrosine phosphorylation. Induces G1 ce
SMLES: BrC1=CC(NC2=NC=NC3=C2C=C(NC)N=C3)=CC=C1
CAS NO: 5852-78-8
Standard In CHIKey: Monoamine Oxidase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C14H12BrN5
M.Wt: 330.18
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/899
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO and to 25 mM in ethanol
Storage: Store at -20℃
Purity: >98%
Chemical Name: N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine