Product Name: Ro 08-2750
Subtitle: antagonist of nerve growth factor (NGF)
Biological Activity: Biological Activity of Ro 08-2750Non-peptide inhibitor of NGF that binds the NGF dimer (KD ~ 1 μM) possibly causing a conformational change. Selectively inhibits binding of NGF to p75NTR at submicromolar concentrations, and to both p75NTR and TrkA at c
SMLES: O=C1NC(N=C2N(C)C3=CC(C=O)=C(C)C=C3N=C21)=O
CAS NO: 60477-34-1
Standard In CHIKey: CaMK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C13H10N4O3
M.Wt: 270.24
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/877
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 50 mM in 1eq. NaOH and to 10 mM in DMSO with gentle warming
Storage: Store at -20℃
Purity: >98%
Chemical Name: 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde