Product Name: Tyrphostin B44, (-) enantiomer
Subtitle:
Biological Activity: Biological Activity of Tyrphostin B44, (-) enantiomerPotent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than the (+) enantiomer. Selective over ErbB2.
SMLES: O=C(/C(C#N)=C/C(C=C1O)=CC=C1O)N[C@H](C)C2=CC=CC=C2
CAS NO: 1047645-82-8
Standard In CHIKey: Pyruvate Dehydrogenase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H16N2O3
M.Wt: 308.34
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/768
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 30 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: (R)-(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide