Herbimycin A
Product Name: Herbimycin ASubtitle: antibiotic and inhibitor of non-receptor tyrosine kinasesBiological Activity: Biological Activity of Herbimycin AAnsamycin antibiotic that acts as a Src family kinase inhibitor. Binds to the SH…
AG 825
Product Name: AG 825Subtitle: Selective ErbB2 inhibitorBiological Activity: Biological Activity of AG 825Selective ErbB2 inhibitor (IC50 values are 0.15 and 19 μM at ErbB2 and ErbB1 respectively). Preferentially triggers p38…
SU 4312
Product Name: SU 4312Subtitle: Biological Activity: Biological Activity of SU 4312Potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 values are 0.8 and 19.4 μM respectively). Selective over…
DMPQ dihydrochloride
Product Name: DMPQ dihydrochlorideSubtitle: Biological Activity: Biological Activity of DMPQ dihydrochlorideA potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine kinase (PDGFRβ) (IC50 = 80…
RR-src
Product Name: RR-srcSubtitle: Biological Activity: Biological Activity of RR-srcTyrosine kinase substrate peptide.SMLES: N/ACAS NO: 130308-48-4Standard In CHIKey: KEOPTZKJOKJEIM-VDNREOAASA-NStearoyl-CoA Desaturase SCD) inhibitorsStandard InChI: InChI=1S/C64H106N22O21/c1-8-31(4)49(86-60(106)42(26-30(2)3)83-55(101)39(14-11-25-74-64(70)71)81-53(99)37(65)12-9-23-72-62(66)67)61(107)82-41(20-22-46(90)91)57(103)85-44(28-47(92)93)59(105)78-34(7)52(98)80-40(19-21-45(88)89)56(102)84-43(27-35-15-17-36(87)1Typrof Compound: Appearance: Formula: C64H106N22O21M.Wt: 1519.7General Tips: For…
AG 494
Product Name: AG 494Subtitle: Potent EGFR-kinase inhibitorBiological Activity: Biological Activity of AG 494Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over ErbB2, PDGFR and…
AG 555
Product Name: AG 555Subtitle: Potent EGFR-kinase inhibitorBiological Activity: Biological Activity of AG 555Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 μM) that displays 50-fold and >140-fold selectivity…
AG 556
Product Name: AG 556Subtitle: EGFR inhibitorBiological Activity: Biological Activity of AG 556Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 1.1 μM). Selective over ErbB2 (IC50 > 500 μM).SMLES: CAS…
Tyrphostin B44, (+) enantiomer
Product Name: Tyrphostin B44, (+) enantiomerSubtitle: Biological Activity: Biological Activity of Tyrphostin B44, (+) enantiomerEpidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.86 μM). Slightly less active than the…
Tyrphostin B44, (-) enantiomer
Product Name: Tyrphostin B44, (-) enantiomerSubtitle: Biological Activity: Biological Activity of Tyrphostin B44, (-) enantiomerPotent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.4 μM), more active than…