Product Name: Methyl 2,5-dihydroxycinnamateSubtitle: Biological Activity: Biological Activity of Methyl 2,5-dihydroxycinnamateErbstatin analog. Inhibitor of EGF receptor-associated tyrosine kinases.SMLES: OC(C(/C=C/C(OC)=O)=C1)=CC=C1OCAS NO: 127243-85-0Standard In CHIKey: BQCNSTFWSKOWMA-GORDUTHDSA-NProteasome inhibitorsStandard InChI: InChI=1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3/b5-2+Typrof Compound: Appearance: Formula:…
Product Name: H-7 dihydrochlorideSubtitle: Biological Activity: Biological Activity of H-7 dihydrochlorideProtein kinase inhibitor. IC50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0…
Product Name: AG 99Subtitle: EGFR inhibitorBiological Activity: Biological Activity of AG 99Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 10 μM) that is selective over insulin receptor kinase. Blocks…
Product Name: GNF-7Subtitle: Type II Bcr-Abl inhibitorBiological Activity: Biological Activity of GNF-7Ras signaling inhibitor; inhibits Ack1 and germinal center kinase (GCK). Suppresses proliferation, and induces cell cycle arrest and apoptosis…
Product Name: NPS-1034Subtitle: MET inhibitorBiological Activity: SMLES: FC1=CC(NC(C2=C(C)N(C)N(C3=CC=C(F)C=C3)C2=O)=O)=CC=C1OC4=CC=NC5=C4C(C6=CC=CC=C6)=CN5CAS NO: 104054-27-5Standard In CHIKey: PDHK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C31H23F2N5O3M.Wt: 551.54General Tips: For obtaining a higher solubility , please warm…
Product Name: Dovitinib (TKI258) LactateSubtitle: Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).Biological Activity: SMLES: FC1=C(C(N)=C(C(O)=N2)C3=NC4=C(N3)C=C(N5CCN(C)CC5)C=C4)C2=CC=C1.CC(O)C(O)=OCAS NO: 1073485-20-7Standard In CHIKey: PAI-1 inhibitorsStandard InChI: Typrof…
Product Name: TP-0903Subtitle: AXL receptor tyrosine kinase inhibitor, anti-cancer agentBiological Activity: SMLES: CN(S(C1=CC=CC=C1/N=C(N2)C(Cl)=CN=C2NC3=CC=C(CN4CCN(CC4)C)C=C3)(=O)=O)CCAS NO: 1446182-94-0Standard In CHIKey: Neprilysin inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C24H30ClN7O2SM.Wt: 516.06General Tips: For obtaining a…
Product Name: CL-387785 (EKI-785)Subtitle: Irreversible inhibiter of EGFRBiological Activity: SMLES: CC#C/C(O)=N/C1=CC(C(NC2=CC=CC(Br)=C2)=NC=N3)=C3C=C1CAS NO: 1439399-58-2Standard In CHIKey: NEDD8-activating Enzyme inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C18H13BrN4OM.Wt: 381.23General Tips: For obtaining a higher…
Product Name: EGF816Subtitle: Novel covalent inhibitor of mutant-selective EGFRBiological Activity: SMLES: CC1=CC(C(NC2=NC3=CC=CC(Cl)=C3N24()CCCCN(C(/C()=C()/CN(C)C)=O)C4)=O)=CC=N1CAS NO: 1202055-34-2Standard In CHIKey: Nampt inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C26H31ClN6O2M.Wt: 495.02General Tips: For obtaining a higher…
Product Name: Fruquintinib(HMPL-013)Subtitle: Potent and selective inhibitor of VEGFR 1, 2, 3Biological Activity: SMLES: CC(O1)=C(/C(O)=N/C)C2=C1C=C(OC3=NC=NC4=CC(OC)=C(OC)C=C43)C=C2CAS NO: 1431985-92-0Standard In CHIKey: MMP inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C21H19N3O5M.Wt: 393.39General Tips: For…