Product Name: (Z)-FeCP-oxindoleSubtitle: Biological Activity: Biological Activity of (Z)-FeCP-oxindoleSelective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 220 nM). Displays anticancer activity (IC50< 1 μM…
Product Name: (E)-FeCP-oxindoleSubtitle: Biological Activity: Biological Activity of (E)-FeCP-oxindoleSelective inhibitor of human vascular endothelial cell growth factor receptor 2 (VEGFR-2) (IC50 = 214 nM). Displays anticancer activity (IC50< 1 μM…
Product Name: BIO-acetoximeSubtitle: Biological Activity: Biological Activity of BIO-acetoximeSelective GSK-3α/β inhibitor (IC50 values are 0.01, 2.4, 4.3 and 63 μM for GSK-3α/β, CDK5/p25, CDK2/cyclin A and CDK1/cyclin B respectively). Induces…
Product Name: TCS 2002Subtitle: GSK -3β inhibitor, potentBiological Activity: Biological Activity of TCS 2002Potent inhibitor of GSK-3β (IC50 = 35 nM). Oral adminstration inhibits cold water stress-induced tau hyperphosphorylation in…
Product Name: 7,8-DihydroxyflavoneSubtitle: Biological Activity: Biological Activity of 7,8-DihydroxyflavoneTyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor (Kd = 320 nM). Inhibits glutamate-triggered apoptosis…
Product Name: HKI 357Subtitle: Biological Activity: Biological Activity of HKI 357Potent, irreversible inhibitor of ErbB2 (HER2) and EGFR (IC50 values are 33 and 34 nM respectively). Suppresses ligand-induced EGFR autophosphorylation…
Product Name: BDNF (human)Subtitle: Biological Activity: Biological Activity of BDNF (human)Member of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth…
Product Name: ER 27319 maleateSubtitle: Biological Activity: Biological Activity of ER 27319 maleateSelective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of FcεRI in rat…
Product Name: TCS 184Subtitle: Biological Activity: Biological Activity of TCS 184Scrambled control peptide for use with TCS 183.SMLES: N/ACAS NO: 297730-17-7Standard In CHIKey: ATP Citrate Lyase inhibitorsStandard InChI: Typrof Compound:…
Product Name: L803-mtsSubtitle: Biological Activity: Biological Activity of L803-mtsSelective peptide inhibitor of glycogen synthase kinase-3 (GSK-3). Produces antidepressive behavior in mice when administered in vivo. Shows no inhibition of PKC,…