Product Name: Tandutinib (MLN518)Subtitle: FLT3 inhibitor,potent and selectiveBiological Activity: Biological Activity of Tandutinib (MLN518)Description Tandutinib (MLN518, CT53518) is a potent antagonist of FLT3 with an IC50 value of 0.22 μM.…
Product Name: PF-573228Subtitle: ATP-competitive FAK inhibitorBiological Activity: Biological Activity of PF-573228Potent and selective inhibitor of focal adhesion kinase (FAK) (IC50 = 4 nM). Displays 50 – 250-fold selectivity for FAK…
Product Name: Tyrphostin 9Subtitle: Selective EGFR/PDGFR inhibitorBiological Activity: Biological Activity of Tyrphostin 9Potent uncoupler of oxidative phosphorylation.SMLES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C=C(C#N)C#NCAS NO: 1379573-88-2Standard In CHIKey: MZOPWQKISXCCTP-UHFFFAOYSA-NKLF inhibitorsStandard InChI: InChI=1S/C18H22N2O/c1-17(2,3)14-8-12(7-13(10-19)11-20)9-15(16(14)21)18(4,5)6/h7-9,21H,1-6H3Typrof Compound: Appearance: Formula: C18H22N2OM.Wt:…
Product Name: Golvatinib (E7050)Subtitle: C-Met/VEGFR-2 inhibitorBiological Activity: Biological Activity of Golvatinib (E7050)Description Golvatinib (E7050) is a dual inhibitor of c-Met and VEGFR-2 with IC50 values of 14 nM and 16…
Product Name: BMS-794833Subtitle: Met/VEGFR-2 inhibitor,potent and ATP-competitiveBiological Activity: SMLES: CAS NO: 1151516-14-1Standard In CHIKey: ERK inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C23H15ClF2N4O3M.Wt: 468.84General Tips: For obtaining a higher solubility ,…
Product Name: GZD824Subtitle: Bcr-Abl inhibitor,novel orally bioavailableBiological Activity: SMLES: CC1=CC=C(C(NC2=CC=C(CN3CCN(C)CC3)C(C(F)(F)F)=C2)=O)C=C1C#CC4=CN=C5C(C=NN5)=C4.CS(=O)(O)=O.CS(=O)(O)=OCAS NO: 1140964-99-3Standard In CHIKey: MAPK_ERK Pathway inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C29H27F3N6O.2CH4O3SM.Wt: 724.77General Tips: For obtaining a higher solubility…
Product Name: Cabozantinib malate (XL184)Subtitle: MET andVEGF receptor2 inhibitorBiological Activity: SMLES: COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F.C(C(C(=O)O)O)C(=O)OCAS NO: 1256589-74-8Standard In CHIKey: Pim inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C32H30FN3O10M.Wt: 635.59General Tips: For obtaining a higher…
Product Name: SKLB1002Subtitle: VEGFR2 inhibitor,potent and ATP-competitveBiological Activity: Biological Activity of SKLB1002Description SKLB1002 is a potent inhibitor of VEGF receptor 2 (VEGFR2) with IC50 value of 32 nM. Targets VEGFR2…
Product Name: A 419259 trihydrochlorideSubtitle: LCK inhibitor, orally availableBiological Activity: Biological Activity of A 419259 trihydrochloridePotent Hck inhibitor (IC50 = 0.43 nM). Also inhibits other Src family kinases (SFKs). Suppresses…
Product Name: A 419259Subtitle: Lck inhibitorBiological Activity: SMLES: CAS NO: 171179-06-9Standard In CHIKey: Toll-like Receptor TLR) inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C29H34N6OM.Wt: 482.62General Tips: For obtaining a higher solubility…