Product Name: ON 146040Subtitle: Biological Activity: SMLES: O=C(NC(C=NC(NC1=CC=C(N2CCN(C)CC2)C=C1)=N3)=C3S/4)C4=CC5=CC=C(()=O)C=C5CAS NO: 883986-34-3Standard In CHIKey: PDK-1 inhibitorsStandard InChI: Typrof Compound: Appearance: Formula: C24H23N7O3SM.Wt: 489.55General Tips: For obtaining a higher solubility , please warm…
Product Name: WH-4-023Subtitle: Lck/Src inhibitor,potent and selectiveBiological Activity: Biological Activity of WH-4-023Potent and selective Lck and Src inhibitor (IC50 values are 2 and 6 nM respectively). Exhibits >300-fold selectivity against…
Product Name: HNGF6ASubtitle: Biological Activity: Biological Activity of HNGF6AHumanin analog; increases glucose stimulated insulin secretion and glucose metabolism in vivo and in vitro. Also enhances glucose sensing in βTC3 cells…
Product Name: KRCA 0008Subtitle: Biological Activity: Biological Activity of KRCA 0008Potent Ack1 and anaplastic lymphoma kinase (ALK) dual inhibitor (IC50 values are 4 and 12 nM respectively). Inhibits lung cancer…
Product Name: A 1070722Subtitle: Biological Activity: Biological Activity of A 1070722Potent glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 0.6 nM for GSK-3α and GSK-3β). Displays high selectivity (> 50-fold) for…
Product Name: PD 161570Subtitle: Biological Activity: Biological Activity of PD 161570Selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR, PDGFR and EGFR respectively). Inhibits FGFR receptor…
Product Name: Src I1Subtitle: Biological Activity: Biological Activity of Src I1Potent, competitive dual site (ATP- and peptide-binding) Src kinase inhibitor (IC50 values are 44 and 88 nM for Src and…
Product Name: human Insulin expressed in yeastSubtitle: peptide hormoneBiological Activity: Biological Activity of human Insulin expressed in yeastEndogenous insulin receptor agonist (Ki = 4.85 nM). Decreases plasma glucose levels, proteolysis,…
Product Name: CGP 52411Subtitle: Biological Activity: Biological Activity of CGP 52411Selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). Also inhibits and reverses the…
Product Name: JNJ 28871063 hydrochlorideSubtitle: Biological Activity: Biological Activity of JNJ 28871063 hydrochloridePotent and selective ErbB receptor family inhibitor (IC50 values are 21, 22 and 38 nM for ErbB4, EGFR…