Name : Human FcRH6/FCRL6 Protein
Product Source :
Recombinant Human FcRH6/FCRL6 Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Leu20-Trp307.[Accession | Q6DN72-1]
Molecular Weight :
The protein has a predicted MW of 32.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human FcRH6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Fc receptor-like 6 (FCRL6), the most recently characterized member of the FCRL family, is a cell surface glycoprotein with tyrosine-based regulatory potential. An extensive survey of human hematopoietic tissues disclosed that FCRL6 expression by NK- and T-cell subpopulations increases as a function of differentiation and is remarkably restricted to mature lymphocytes with cytotoxic capability.
Synonyms :
Fc receptor-like protein 6;FcR-like protein 6;Fc receptor homolog 6;IFGP6;FLJ16056
References & Citations :
(1)Schreeder DM, Pan J, Li FJ, Vivier E, Davis RS. FCRL6 distinguishes mature cytotoxic lymphocytes and is upregulated in patients with B-cell chronic lymphocytic leukemia. Eur J Immunol. 2008 Nov;38(11):3159-66. doi: 10.1002/eji.200838516. PMID: 18991291; PMCID: PMC2742621.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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