Name : Human FcRH6 /FCRL6 Protein
Product Source :
Recombinant Human FcRH6 /FCRL6 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu20-Trp307.[Accession | Q6DN72-1]
Molecular Weight :
The protein has a predicted MW of 58.4 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt.-80°C for 3-6 months after reconstitution.2-8°C for 2-7 days after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human FcRH6 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human FcRH6 is greater than 95% as determined by SEC-HPLC.
Background :
A surprising number of Fc receptor (FcR) relatives have been recognized recently with the potential capacity to modulate innate and adaptive immune responses. The six human FcR homologs (FcRH1-6), which belong to a phylogenetically conserved gene family, have variable numbers of extracellular immunoglobulin domains of five different subtypes. All but one of these new receptors, FcRH6, are expressed on B cells at different stages in differentiation.
Synonyms :
FcR-like protein 6; FcRL6; FcRH6; IFGP6; Fc receptor-like 6; FLJ16056
References & Citations :
(1) Davis RS, Ehrhardt GR, Leu CM, Hirano M, Cooper MD. An extended family of Fc receptor relatives. Eur J Immunol. 2005 Mar;35(3):674-80. doi: 10.1002/eji.200425886. PMID: 15688344.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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