Name : Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling)
Product Source :
Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu29-Ala216.[Accession | P43489]
Molecular Weight :
The protein has a predicted MW of 46.8 kDa. Due to glycosylation, the protein migrates to 72-75 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Biotinylated Human OX40 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
Synonyms :
CD134; OX40; OX40L receptor; TNFRSF4; ACT-135; Ly-70; OX40 homologue; TXGP1L; IMD16
References & Citations :
(1)Al-Shamkhani A , Mallett S , Brown M H , et al. Affinity and Kinetics of the Interaction between Soluble Trimeric OX40 Ligand, a Member of the Tumor Necrosis Factor Superfamily, and Its Receptor OX40 on Activated T Cells[J]. Journal of Biological Chemistry, 1997, 272(8):5275-5282.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
GDF-8 Protein
CEACAM5 Protein
Popular categories:
Ubiquitin-Conjugating Enzyme E2 H
Serine/Threonine Kinase 40