Name : FITC-Compatible Human BCMA/TNFRSF17 Protein
Product Source :
Recombinant FITC-Compatible Human BCMA/TNFRSF17 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Met1-Ala54.[Accession | Q02223-1]
Molecular Weight :
The protein has a predicted MW of 35.9 kDa. Due to glycosylation, the protein migrates to 37-48 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE FITC-Compatible Human BCMA on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of FITC-Compatible Human BCMA is greater than 95% as determined by SEC-HPLC. FACS Data Use 100 μl FITC-Compatible Human BCMA (1 μg/ml) to detect the positive rate of 1×106 anti-BCMA CAR cells. Non-transfected 293T cells and FITC-Labeled irrelevant protein (100 μl, 1 μg/ml) were served as negative control.
Background :
B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).
Synonyms :
CD269; TNFRSF17; BCMA; BCM; TNFRSF13A
References & Citations :
(1)Bossen C , Schneider P. BAFF, APRIL and their receptors: Structure, function and signaling[J]. Seminars in Immunology, 2006, 18(5):0-275.D
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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