Name : FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein
Product Source :
Recombinant FITC-Labeled Human CD27 Ligand/CD70 Trimer Protein is expressed from HEK293 with His tag at the N-Terminus. It contains Leu50-Pro193.[Accession | P32970-1]
Molecular Weight :
The protein has a predicted MW of 51.8 kDa. Due to glycosylation, the protein migrates to 63-68 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE
Formulation :
Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE FITC-Labeled Human CD27 Ligand Trimer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
Background :
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Synonyms :
CD70 molecule; CD70; TNFSF7; CD27 Ligand; CD27-L; CD27LG; Ki-24 antigen; TNFSF7G
References & Citations :
(1)Buchan S L , Rogel A , Al-Shamkhani A. The immunobiology of CD27 and OX40 and their potential as targets for cancer immunotherapy[J]. Blood, 2017:blood-2017-07-741025.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
LRRC15 Proteinsite
Semaphorin-4D/SEMA4D Proteinweb
Popular categories:
Oxidative Stress Responsive Kinase 1 (OXSR1)
Fibroblast Growth Factor 21 (FGF-21)