Name : Human CKMT1A Protein

Product Source :
Recombinant Human CKMT1A Protein is expressed from Baculovirus-Insect Cells with His tag at the N-terminus. It contains Ala40-His417.[Accession | P12532-1]

Molecular Weight :
The protein has a predicted MW of 44.60 kDa same as Tris-Bis PAGE result.

Endotoxin Level :
Less than 1EU per μg by the LAL method.

Purity :
> 95% as determined by Tris-Bis PAGE

Formulation :
Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM NaCl (pH 8.5).

Reconstitution :

Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Product Concentration :
Tris-Bis PAGE Human CKMT1A on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

Background :
Mitochondrial creatine kinase 1A (CKMT1A) is a mitochondrial protein that exists on the outer surface of the inner membrane of mitochondria. Its main function is to facilitate the transfer of phosphocreatine (PCr) energy across mitochondria by transferring phosphate groups from mitochondrial ATP to creatine (Cr).

Synonyms :
Mia-CK; Mia CK; U-MtCK; U MtCK; CKMT; CKMT1B

References & Citations :
Yang M, Liu S, Xiong Y, Zhao J, Deng W. An integrative pan-cancer analysis of molecular characteristics and oncogenic role of mitochondrial creatine kinase 1A (CKMT1A) in human tumors. Sci Rep. 2022 Jun 15;12(1):10025. doi: 10.1038/s41598-022-14346-z. PMID: 35705641; PMCID: PMC9200842.

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