Name : Human ERK2 Protein
Product Source :
Recombinant Human ERK2 Protein is expressed from Baculovirus-Insect Cells with His tag at the C-terminus. It contains Met1-Ser360.[Accession | P28482]
Molecular Weight :
The protein has a predicted MW of 42.91 kDa same as Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM Nacl, 10% glycerol (pH 8.0).
Reconstitution :
Storage and Stability :
Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human ERK2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human ERK2 is greater than 95% as determined by SEC-HPLC.
Background :
Extracellular signal-regulated protein kinase 2 (ERK2) plays many vital roles in cellular signal regulation. Phosphorylation of ERK2 leads to propagation and execution of various extracellular stimuli, which influence cellular responses to stress. The final response of the ERK2 signaling pathway is determined by localization and duration of active ERK2 at specific target cell compartments through protein-protein interactions of ERK2 with various cytoplasmic and nuclear substrates, scaffold proteins, and anchoring counterparts.
Synonyms :
MAPK 1; MAPK1; ERK-2; p42-MAPK; p42 MAPK; MAPK 2; PRKM1; PRKM2
References & Citations :
Lee S, Bae YS. Monomeric and dimeric models of ERK2 in conjunction with studies on cellular localization, nuclear translocation, and in vitro analysis. Mol Cells. 2012 Apr;33(4):325-34. doi: 10.1007/s10059-012-0023-4. Epub 2012 Mar 23. PMID: 22450690; PMCID: PMC3887802.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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