Name : Human TAFA2/FAM19A2 Protein
Product Source :
Recombinant Human TAFA2/FAM19A2 Protein is expressed from HEK293 with hFc tag at the N-terminus. It contains Ala31-His131.[Accession | Q8N3H0-1]
Molecular Weight :
The protein has a predicted MW of 36.74 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin Level :
Less than 1EU per μg by the LAL method.
Purity :
> 95% as determined by Tris-Bis PAGE> 95% as determined by HPLC
Formulation :
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution :
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage and Stability :
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3-6 months after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Product Concentration :
Tris-Bis PAGE Human TAFA2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. SEC-HPLC The purity of Human TAFA2 is greater than 95% as determined by SEC-HPLC.
Background :
Tafa is a family of small secreted proteins with conserved cysteine residues and restricted expression in the brain. It is composed of five highly homologous genes referred to as Tafa-1 to -5. FAM19A2/TAFA-2 induces skeletal stem cell migration through the activation of Rac1-p38 signaling and is highly abundant in the central nervous system and MIP1α regulates energy balance.
Synonyms :
TAFA2; FAM19A2; TAFA-2
References & Citations :
Okada J, Yamada E, Saito T, Ozawa A, Nakajima Y, Pessin JE, Okada S, Yamada M. Analysis of FAM19A2/TAFA-2 function. Physiol Behav. 2019 Sep 1;208:112581. doi: 10.1016/j.physbeh.2019.112581. Epub 2019 Jun 17. PMID: 31220516.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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