Product Name: Imatinib (STI571)
Subtitle: Protein-tyrosine kinase inhibitor
Biological Activity: Biological Activity of Imatinib (STI571)Description Imatinib is a selective inhibitor of protein-tyrosine kinase with IC50 values of 0.1, 0.1 and 0.025 μM, respectively against PDGF receptor, c-Kit and Abl. Targets PDGF receptor c-Kit Abl
SMLES: CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
CAS NO: 848318-25-2
Standard In CHIKey: KTUFNOKKBVMGRW-UHFFFAOYSA-NRaf inhibitors
Standard InChI: InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)
Typrof Compound:
Appearance:
Formula: C29H31N7O
M.Wt: 493.6
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/312
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Limited solubility
Storage:
Purity: >98%
Chemical Name: 4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide