Product Name: CP-673451
Subtitle: PDGFRα/β inhibitor,potent and selective
Biological Activity: Biological Activity of CP-673451Description CP-673451 is a selective inhibitor of PDGFRα/β with IC50 values of 10 nM/1 nM,respectively. Targets PDGFRβ PDGFRα c-Kit VEGFR1 VEGFR2 IC50 1 nM 10 nM 252 nM 450 nM 450 nM
SMLES: COCCOC1=CC2=C(C=C1)N(C=N2)C3=NC4=C(C=CC=C4N5CCC(CC5)N)C=C3
CAS NO: 1632032-53-1
Standard In CHIKey: Ribosomal S6 Kinase RSK) inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H27N5O2
M.Wt: 417.52
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/319
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 1-[2-[5-(2-methoxyethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine