Product Name: GW441756
Subtitle: TrkA inhibitor,potent and selective
Biological Activity: Biological Activity of GW441756Potent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC50 = 2 nM). Displays > 100-fold selectivity over a range of other kinases.
SMLES: CN1C=C(C2=CC=CC=C21)C=C3C4=C(C=CC=N4)NC3=O
CAS NO: 723249-01-2
Standard In CHIKey: Calcium Channel inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C17H13N3O
M.Wt: 275.3
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/340
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 15 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one