Product Name: SAR131675
Subtitle: VEGFR3 inhibitor,selective and ATP-competitve
Biological Activity: Biological Activity of SAR131675Description SAR131675 is an inhibitor of VEGFR3 with IC50/Ki of 23 nM/12 nM, respectively. Targets VEGFR3 IC50 23 nM (Ki=12 nM)
SMLES: CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#CC(C)(COC)O)C(=O)NC)N
CAS NO: 252557-97-4
Standard In CHIKey: CFTR inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C18H22N4O4
M.Wt: 358.39
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/345
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: 2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide