Product Name: GS-9973
Subtitle: Syk inhibitor, orally bioavailable and selective
Biological Activity: Biological Activity of GS-9973Description GS-9973 is an orally bioavailable, selective inhibitor of Syk with IC50 value of 7.7 nM. Targets Syk IC50 7.7 nM
SMLES: [O-][N+](C1=C(N=C(N=C1NC2CCCC2)SC)NC3CCCC3)=O
CAS NO: 210344-95-9
Standard In CHIKey: HCN Channel inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C23H21N7O
M.Wt: 411.46
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/1/397
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble in DMSO > 10 mM
Storage:
Purity: >98%
Chemical Name: N4,N6-dicyclopentyl-2-(methylthio)-5-nitropyrimidine-4,6-diamine