Product Name: GSK2578215A
Subtitle:
Biological Activity: Biological Activity of GSK2578215APotent LRRK2 inhibitor (IC50 values are 8.9 and 10.1 nM for LRRK2[G2019S] mutant and wild-type LRRK2 respectively). Displays selectivity for LRRK2 over a panel of 460 other kinases. Blocks Ser910 and Ser935 phosphorylatio
SMLES: FC1=NC=CC(C2=CC=C(C(C(NC3=CC=CN=C3)=O)=C2)OCC4=CC=CC=C4)=C1
CAS NO: 173441-26-4
Standard In CHIKey: Glucokinase inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C24H18FN3O2
M.Wt: 399.42
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/584
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 100 mM in DMSO
Storage: Store at RT
Purity: >98%
Chemical Name: 5-(2-Fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinylbenzamide