Product Name: AG 494
Subtitle: Potent EGFR-kinase inhibitor
Biological Activity: Biological Activity of AG 494Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50 = 0.7 μM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively).
SMLES:
CAS NO: 4800-94-6
Standard In CHIKey: SGK inhibitors
Standard InChI:
Typrof Compound:
Appearance:
Formula: C16H12N2O3
M.Wt: 280.28
General Tips: For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.PubMed ID:http://jpet.aspetjournals.org/content/275/2/798
Shipping Condition: Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.
Solubility: Soluble to 5 mM in ethanol and to 50 mM in DMSO
Storage: Desiccate at +4℃
Purity: >98%
Chemical Name: (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide